A community for people who want to remain as healthy as possible as we age.

Diabetes Prevention Programs Improve Health Profiles

(Emory Health Sciences) A new study ... shows that lifestyle modification programs modeled on diabetes prevention programs (DPP) trials not only achieved weight reduction, but also additional metabolic benefits -specifically, reductions in blood sugar, blood pressure, and cholesterol levels. The researchers compiled data from 44 published studies with nearly 9,000 adults participating in DPP conducted in US communities, clinics, and through online media…
·         "on average, participants in the 44 included studies were similar to participants in the original DPP trial, and achieved less weight loss (3.8 vs. 6.8kg), but similar improvements in glucose, blood pressure, and cholesterol reductions; and
·         "programs with a maintenance component (keeping contact with participants even after the core program sessions are complete) were associated with larger benefits."…
The authors conclude: "According to our findings, there is no difference in outcomes based on who or where DPP programs are delivered, and improvement in other cardio-metabolic factors suggests the program may be especially cost-effective. These types of interventions can yield great results for diabetes prevention if distributed nationally."
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Flu vaccine may reduce risk of death for type 2 diabetes patients

(Imperial College London) The flu vaccine may reduce the likelihood of being hospitalised with stroke and heart failure in people with type 2 diabetes, according to new research…
The scientists found that, compared to patients who had not been vaccinated, those who received the jab had a 30 per cent reduction in hospital admissions for stroke, 22 per cent reduction in heart failure admissions and 15 per cent reduction in admissions for pneumonia or influenza.
Furthermore, people who were vaccinated had a 24 per cent lower death rate than patients who were not vaccinated.
The team also found a 19 per cent reduction in hospital admissions for heart attack among vaccinated type 2 diabetes patients during the flu season, however this finding was not statistically significant.
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Greater intake of dietary omega-3 fatty acids associated with lower risk of diabetic retinopathy

 (The JAMA Network Journals) In middle-aged and older individuals with type 2 diabetes, intake of at least 500 mg/d of dietary long-chain ω-3 polyunsaturated fatty acids, easily achievable with 2 weekly servings of oily fish, was associated with a decreased risk of sight-threatening diabetic retinopathy [(DR)], according to a study…
Aleix Sala-Vila, D.Pharm., Ph.D., of the Lipid Clinic, Barcelona, and colleagues conducted a prospective study within the randomized clinical trial Prevencion con Dieta Mediterranea (PREDIMED), testing Mediterranean diets supplemented with extra virgin olive oil or nuts vs a control diet for primary cardiovascular prevention…
After adjusting for age, sex, intervention group, and lifestyle and clinical variables, participants meeting the LCω3PUFA recommendation at baseline (500 mg/d or greater) compared with those not fulfilling this recommendation (less than 500 mg/d) showed a 48 percent relatively reduced risk of incident sight-threatening DR.
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Meet the brothers who reversed their father's diabetes

(The Telegraph) By 2013 complications had set in: [Geoff Whitington] contracted Charcot Foot – a progressive and gory destruction of the joint – which, in addition to diabetes-related ulcers on his other foot, meant a grave risk of amputation.
He fell into near-depression, withdrawing from visiting his sons and grandchildren. Consigned to an early death from diabetes, he even took to writing a will…
[Son] Anthony, a freelance filmmaker, and [son] Ian…, a cameraman, hatched a plan to help their father. The pair also decided to make a documentary, Fixing Dad, to chart Geoff’s progress…
The brothers researched the disease - which affects more than 3.6 million people in the UK - drew up a three-pronged attack on Geoff’s fitness, nutritional and mental hurdles, and set a daunting target: that the three of them would complete a the 100-mile Prudential RideLondon-Surrey cycling event in July 2014…
The journey wasn’t always easy – various explosive arguments are captured at points where the pressure felt too much – but just nine months after he began the programme, Geoff completed the 100-mile ride through London.
Then, in February last year came the news they’d always wished for. The diabetes had been successfully 'resolved’. Geoff was fixed.
Community: Here’s another example: “Reversing diabetes requires lifestyle change.” Bear in mind that the same lifestyle elements that can reverse diabetes can prevent you from getting it in the first place.
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Longer survival likely to be reason for increased numbers with diabetes, rather than increased incidence

(Diabetologia) Overall incidence of type 2 diabetes has stabilised over recent years, according to a new study… , whilst mortality has declined, suggesting that increasing prevalence of the disease within the population may be attributed not to increasing numbers but to longer survival of patients with diabetes. The findings were not equal across the population, however: significant differences are noted based on gender, age, and socioeconomic status…
The authors conclude: "Despite improved mortality rates, type 2 diabetes confers an excess risk of death compared with the non-diabetic population...there is still scope to address the increased mortality associated with diabetes."
They add: "Major inequalities by age, sex and socioeconomic status in type 2 diabetes incidence and mortality indicate that effective approaches to treatment and control will need to address existing inequalities."
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Fluoride consumption linked to diabetes using mathematical models

(Case Western Reserve University) Water fluoridation prevents dental cavities, which are a costly public health concern. But despite the benefits supplemental water fluoridation remains a controversial subject. Some indicate it may cause long term health problems, but studies reporting side effects have been minimal or inconclusive. The long-term effects of ingested fluoride remain unclear.
A recent study … examined links between water fluoridation and diabetes…
Kyle Fluegge, PhD, … used mathematical models to analyze publicly available data on fluoride water levels and diabetes incidence and prevalence rates across 22 states. He also included adjustments for obesity and physical inactivity collected from national telephone surveys to help rule out confounding factors. Two sets of regression analyses suggested that supplemental water fluoridation was significantly associated with increases in diabetes between 2005 and 2010.
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Can Statins Cause Diabetes?

(Well, New York Times) All medications have side effects, and numerous studies have shown that cholesterol-lowering statin drugs are linked to a small increase in the risk of Type 2 diabetes, even as they reduce the risk of heart attacks.
The higher the dose of a statin, the greater the diabetes risk, said Dr. Eric Topol, director of the Scripps Translational Science Institute and chief academic officer at Scripps Health. But many heart doctors, including Dr. Mary Norine Walsh, president-elect of the American College of Cardiology, say concern about diabetes should not deter patients from taking statins “if you fall into the higher risk category” for heart disease.
On the other hand, someone who has never had heart disease and who has high cholesterol but no other risk factors is less likely to derive benefit from a statin drug while still facing the risk of diabetes, Dr. Topol said, adding, “There you have a very tight benefit-to-risk ratio.”
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A Dietary Approach to Managing Type 2 Diabetes

(Diabetes In Control) Various studies suggest the use of a Mediterranean diet in patients with diabetes…
A meta-analysis done by [Efi] Koloverou and colleagues found that there is a 23% reduction in the risk of developing diabetes, regardless of world region and patient’s health status. In the PRE-DIMED trial, patients on a Mediterranean diet had a 40% reduction in the risk of developing diabetes. Additionally, when obtaining glycemic control in patients with diabetes, it was found that a Mediterranean diet with low carbohydrate content had a higher rate of remission in patients with diabetes, when compared to low-fat content.
Recently, [Flavie] Letois and colleagues studied the effects of a Mediterranean diet on mortality in the elderly population…
The association between the 10-year mortality risk and dietary patterns showed better survival in those individuals who consumed at least 1 fruit and 1 vegetable per day … or at least 4 servings per week…, consumed fish at least 2 servings per week… It was also found that meat consumption in servings greater than 1 per day had a negative effect on survival… Finally, the use of olive oil was found to be inversely correlated with mortality risk only in women…
These findings highlight the potential benefits of a Mediterranean diet in the elderly (>65 y/o)…
More studies should be done to focus on the association between survival, diet, and healthy behaviors in patients with diabetes to get more evidence for the use of this diet.
Community: Again, if the Mediterranean diet can cause remission of diabetes, it could prevent contracting it in the first place.
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Involving Patient's Partner May Improve Diabetes Control

(Medscape) For adults with poorly controlled type 2 diabetes, a behavioral telephone intervention that includes their spouse or other committed partner may make a difference, new research shows…
"It is likely to be beneficial in several ways to involve partners who are willing… Both partners need to agree, and the intervention should be aimed at helping them see how diabetes affects each of them and their relationship," [Paula M Trief, PhD] told Medscape Medical News.
The idea, she said, is "to strive toward opening up communication about how they can help each other, not for the partner to be a watchdog but to be a supportive coach."
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To Fight Off Diabetes, Latina Women Find Power In A Group

(Shots, NPR) Beatrice Sanchez and Mariana Arias drive around their city, Winston-Salem, N.C., in search of a very specific population of residents: Latinos with prediabetes.
The two women, both bilingual and Hispanic, are recruiting participants for a Type 2 diabetes prevention study called "La Comunidad," a lower-cost local version of the landmark Diabetes Prevention Program trial that staved off diabetes through changes in diet and physical activity in about 50 percent of study participants.
The results of that study suggested it was possible to fight a disease that affects about 29 million Americans without drugs and their side effects. It was more effective than using a common diabetes drug called metformin, which cut that number by just 30 percent…
The ultimate goal of studies like La Comunidad, Vitolins says, is to determine whether group-based techniques are helpful from both a health and medical reimbursement perspective. In March, the Centers for Medicare and Medicaid Services (CMS) announced that Medicare would cover preventive programs that meet the Centers for Disease Control and Prevention's (CDC) requirements, such as data reporting.
Vitolins agrees that community-level programs must have good data to support their use. "We're testing before we say everyone who's in the Latino population should use this approach," she says. "We want it to be effective."
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Treating diabetes app, software gain international acclaim

(University of Virginia) Like many good ideas, the idea behind Ed Deng's diabetes management app began at home.
The University of Virginia alumnus, who graduated in 2000 and now lives in Taiwan, has watched his parents and grandparents painstakingly navigate the daily challenges that come with Type II diabetes, knowing that he, too, is at risk for the disease. He saw firsthand how important it is for patients to track their illness throughout each day and how cumbersome and inefficient that monitoring process could be…
"I realized that a cloud-based solution, along with a mobile app, could help alleviate that shortage and provide more real-time feedback that patients are lacking."
Deng was well-equipped to create that solution. Growing up in a family of physicians – his father and brother each attended UVA's School of Medicine – he was familiar with the medical industry. His own studies at UVA's McIntire School of Commerce led to a career in Lehman Brothers' Silicon Valley office, where he was involved with several companies developing mobile technology.
In 2013, he used those skills to found H2 Inc. and launch a free Health2Sync mobile app for diabetes management…
"Patients are telling us that the app has really helped them lower and control their blood sugar, understand why their data trends a certain way and decrease incidents," Deng said. "Hearing that has just been awesome."
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Stair climbing after meals improves blood sugar levels in type 2 diabetes, study reports

(Diabetes.co.uk) Older adults with type 2 diabetes who perform three minutes of stair climbing at one and two hours after a meal have lower post-meal blood sugar levels, according to new research…
Each stair exercise comprised six continuous repetitions of climbing to a second floor at a rate of 80-110 steps/min followed by walking down slowly to the first floor.
In the second session, participants consumed the breakfast as normal but then rested without interruption for the whole 180 minutes…
There were minimal differences in blood sugar levels between the two groups at 60 minutes after the meal, but the exercise group experienced lower blood glucose as the session became longer.
Blood glucose levels at 150 minutes after the meal (30 minutes after the second stair exercise), in particular, were significantly lower than during the rest session.
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No Significant Difference Found Between Glucose-Lowering Drugs for Risk of Death

(The JAMA Network Journals) Among nearly 120,000 adults with type 2 diabetes, there were no significant differences in the associations between any of 9 available classes of glucose-lowering drugs (alone or in combination) and the risk of cardiovascular or all-cause mortality, according to a study…
The authors note that a central finding in this meta-analysis was that despite more than 300 available clinical trials involving nearly 120,000 adults, there was limited evidence that any glucose-lowering drug stratified by coexisting treatment prolonged life expectancy or prevented cardiovascular disease.
"Metformin was associated with lower or no significant difference in HbAlC levels compared with any other drug classes. All drugs were estimated to be effective when added to metformin. These findings are consistent with American Diabetes Association recommendations for using metformin monotherapy as initial treatment for patients with type 2 diabetes and selection of additional therapies based on patient-specific considerations," the researchers write.
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Insulin price spike leaves diabetes patients in crisis

(Montana Standard) A massive spike in insulin prices is causing a health crisis for millions of diabetes patients who depend on the lifesaving drug, doctors say.
Now, after years of rapid increases having nothing to do with available supply and not matched elsewhere in the world, those in the U.S. insulin supply chain are blaming each other.
Tens of thousands of medical professionals are engaged in an intricate therapeutic ballet performed to protect the health, limbs, and lives of the almost 30 million people in the U.S. suffering from diabetes.
But their efforts have been dramatically complicated by the soaring increase in the cost of insulin. They find themselves balancing the cost of the essential medication and their patients' ability to pay.
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