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Chrondroitin Outperforms Celecoxib in Knee Osteoarthritis Study

(American College of Rheumatology) For the first time, chondroitin sulfate has been more successful than celecoxib in reducing the long-term progression of knee osteoarthritis (OA), according to new research findings…
Chondroitin sulfate, more commonly called chondroitin, has long been the subject of debate when it comes to its usefulness in treating OA. Canadian researchers recently explored how this treatment would affect how OA progresses as well as how it compared to celecoxib (Celebrex®) -- an often used first-line symptomatic treatment in the disease.
"We felt the present study was necessary in order to establish -- using the most recent imaging technology available, quantitative magnetic resonance imaging (qMRI) -- whether chondroitin sulfate can truly and effectively reduce the progression of the disease in patients suffering from knee OA," says lead investigator in the study, Jean-Pierre Pelletier, MD…
At both one and two years, the researchers found a better reduction of cartilage loss in the whole knee, and more particularly in the inner half, of the participants on chondroitin when compared to those on celecoxib. Additionally, there was a decrease in synovial membrane thickness in some of the participants on chondroitin, showing far better results for this group.
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