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Tau May Be Link Between Traumatic Brain Injury and Neurodegeneration

(MedPage Today) A misshapen form of tau may be responsible for the link between traumatic brain injury (TBI) and neurodegenerative disease, but a novel antibody was able to selectively detect and destroy the toxic protein, according to early-stage research.
Brain tissue from patients with chronic traumatic encephalopathy (CTE) was flush with cis P-tau, while healthy control brains had none of the misshapen protein, according to Kun Ping Lu, MD, PhD, of Beth Israel Deaconess Medical Center and Harvard Medical School in Boston, and colleagues…
In addition to developing a humanized monoclonal antibody, Lu said his group also wants to study the utility of cis P-tau levels in cerebrospinal fluid and blood as a biomarker for detecting TBI and potentially mild cognitive impairment in early Alzheimer's.
Community: Might this procedure become a treatment for Alzheimer’s, as well?
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