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Bile – Not Acid – Is Bad Guy in Triggering Precancerous Condition Associated With Reflux Disease

(Science Daily)  For many people with gastroesophageal reflux disease or GERD, acid reflux drugs are the answer to their woes, curbing the chronic heartburn and regurgitation of food or sour liquid characteristic of the disorder. But when it comes to Barrett's esophagus, a condition commonly found in people with GERD, acid control may be less important than beating back another bodily fluid -- bile.
A new study … shows that bile -- a digestive fluid that leaks backwards from the stomach into the esophagus along with acid in patients with GERD -- plays a critical and previously unrecognized role in the development of Barrett's esophagus. Study authors say the findings provide new avenues for the prevention and treatment of the condition, which is the only known cause of a rare but often deadly type of cancer
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