A community for people who want to remain as healthy as possible as we age.

Naproxen Reduces Tumors in a Mouse Model of Colon Cancer, Researchers Report

(Science Daily) Numerous studies show that non-steroidal anti-inflammatory drugs (NSAIDs) reduce the risk of colon cancer. However, animal studies testing the NSAID naproxen or its derivative, NO-naproxen, have focused primarily on chemically-induced tumor formation. Now, researchers at Fox Chase Cancer Center find that naproxen and NO-naproxen reduce tumor formation in a strain of mutant mice that spontaneously develop colon tumors. The data also suggest that naproxen blocks a gatekeeper step that initiates tumor formation…
"There is a major effect on the very small lesions, about a 90% reduction in the mutant mice treated with naproxen compared with control animals," says [Margie Clapper, PhD]. "That tells us this drug may be very appropriate for intervening early in people, far in advance of the development of large tumors. We might be able to have a significant impact on the very early and small lesions, thus reducing the morbidity associated with the disease."
[Click the title, above, to post a comment.]

0 comments:

Post a Comment

Please do not give advice. We can best help each other by telling what works for us, not what we think someone else should do.